@massivelyop If it's an overall IP, I'd say Star Trek is underutilized in the gaming industry (ompared to the other very famous space saga who gets tons of games).
If that's a MMO IP that has not been derived enough, I'd go with Guild Wars. Apart from the two MMOs, there is nothing I can think of based on this universe (not even a TTRPG... Hell, even TSW did get one!)