Maps from Flightradar 24 show that air travel between Europe and Asia is increasingly becoming a challenge. There are only two corridors left which allow uninterrupted travel. Extending the current war to Turkey, Azerbaijan and Oman - three countries which already have to deal with Iranian drones and missiles - will further complicate matters.
@Tendar keep in mind, that there is a third route via the Bering Strait and Alaska, particularly useful when flying from East Asia to Europe. It’s a bit difficult to track because very far north.