An ideal pickup line, to me, is one that has a chance of establishing a rapport over a shared interest, while not coming across as *too* weird/creepy in the event the other person doesn't actually share that interest.

For example:
"You remind me of the babe."

For another example:
"Hey, did you know the critically acclaimed MMORPG Final Fantasy XIV Online has an expanded free trial up to level 70, now including the award-winning Heavensward and Stormblood expansions, with no restrictions on playtime?"