I suffer from a condition known as Non 24-Hour Sleep Wake Disorder, which from my experience is not something most people seem to have heard of before. So, I thought for the sake of spreading awareness I might do a thread explaining what exactly this disorder IS and how it works #n24 #non24 #non24hoursleepwakedisorder

What is Non 24-Hour Sleep Wake Disorder?

For your average person, their internal circadian rhythm (which controls when you wake up, how long you stay awake for, when you start to get tired, when you go to sleep, and how long you sleep for) is set to a 24 hour cycle, meaning you'll go to bed and wake up at about the same time every day. There may be some variance; you might stay up later and sleep in later on weekends for example, but for the most part you wake in the morning and sleep at night.

The cycle of people with N24 however is, well, non-24 hour. The combined time that people with N24 stay awake and sleep for adds up to either more or less than 24 hours (more commonly over 24 hours).

Let's imagine for example someone who has n24 with a 25 hour cycle. They wake up at 7 AM, go about their day for the next 16 hours, and go to bed at 11 PM. They sleep for 9 hours, adding up to a total of 25 hours.

They wake up the next day, but because of the extra hour in their cycle today they wake up at 8 AM instead of 7 AM. They go about their day for 16 hours, sleep at midnight, and wake up the next morning after 9 hours of sleep at 9 AM. After another 3 days they will be waking up at 12 PM and going to bed at 4 AM. After a week they will be waking up at 4 PM and going to bed at 8 AM. Eventually once enough time has passed it will loop around fully and they will wake at 7 AM and sleep at 11 PM again.

Letting the schedule drift forward like this uninterrupted is called "free running"

(though N24 is rarely as consistent as this example; our cycles don't advance precisely the same amount every day, and its not at all uncommon for there to be sudden multi-hour jumps forward in your cycle, or for your cycle to remain at a fixed wake up and sleep time for a number of days before drifting again, and sometimes it will even move backwards by an hour or two. It's all kind of messy).

OK, so why not just not free run?

Trying to adhere to a 24 hour cycle for someone with n24 is just as difficult as trying to adhere to a non 24 hour cycle would be to someone without n24. Just going to bed an hour earlier or sleeping an hour less would not work for our hypothetical n24 sufferer; the body's sense of when it SHOULD be asleep will keep moving even if you do force yourself to sleep outside of it.

The effects of this get worse as the body's internal clock gets more out of sync with the time they're trying to force themselves to wake up. Let's say our example person with a 25 hour schedule tries to set alarms to get up at 7 AM and go to bed at 11 PM every day. They let their schedule sync up to this time before hand, so there's no issues the first day. The 2nd day their body wants to wake up at 8 AM, but their alarm wakes them up at 7 AM. They feel sleep deprived by 1 hour.
That night they might have trouble getting to sleep at their 11 PM goal. They're not that tired yet, because their body wants to be asleep at midnight. The next morning, 7 AM, feels like 2 hours of sleep deprivation. At 11 PM they lay in bed for an hour or two before managing to fall asleep. They wake up on the third day feeling 3 hours less rested. They might take a nap that afternoon from the tiredness, but it doesn't feel restful and it makes getting to sleep at 11 PM that night even harder.
This is clearly unsustainable long term. Forcing yourself to wake up before your circadian rhythm is ready feels like getting less sleep than your body needs, and similarly trying to force yourself to sleep before your circadian rhythm is ready to is difficult, and the resulting sleep rarely feels truly restful because the body is not ready to be asleep at this time. For someone without N24 it would be like trying to wake up at 2 AM every night, or to try and sleep at 1 PM when you woke at 7 AM.

So it's like insomnia / narcolepsy / insert non circadian rhythm sleep disorder here?

Not really. While other sleep disorders effect the ability to fall asleep, how often and when you fall asleep, how long you stay asleep for, how rested you feel after sleeping etc., circadian rhythm disorders are disorders of the internal body clock rather than of the sleep itself. If I'm allowed to free run without interruptions, I can fall asleep easily, sleep a healthy 7 to 9 hours, and feel rested after.

Isn't N24 something only blind people suffer from?

If you've heard of N24 before this post, it may be from the fact that it effects around 50-70% of the totally blind. While it is a more common condition among the blind, it can develop in the sighted population as well (such as myself).

So what are the knock-on effects of this disorder?

Being out of sync with the sleep-wake cycle the majority of the population operate off of understandably causes some problems. Holding down employment is difficult for sufferers of N24. Most jobs will require you to clock in and out at a consistent time, and we are not able to force ourselves into these schedules without suffering massive sleep deprivation as a result.

There are some jobs with more flexible work from home schedules, usually software related jobs, but jobs with a truly flexible schedule are uncommon, and the ability to work in those fields often requires qualifications and knowledge which are inaccessible because schooling itself requires a degree of adherence to a 24 hour schedule. I don't know what if any studies have been done on this, but from purely anecdotal evidence, the majority of people with N24 I've seen have been unemployed.

I myself am unemployed and reliant on disability payments because of my N24.

N24 makes having a social / romantic life difficult too: you're often going to be out of sync with the schedules of the people around you, and it can be hard to predict exactly when you're going to be awake or asleep ahead of time for scheduling meetups or events. My circle of friends are all online across the world in different time zones because it's difficult to form friendships locally while free running.

Scheduling other things such as doctor's appointments ahead of time is also difficult, and often I end up having to go to them sleep deprived because I guessed wrong when booking the appointment 2 weeks ago. You have to plan around when the opening and closing times of stores overlap with your cycle because they'll be closed when you're in a nocturnal phase. Similarly you have to estimate when buying groceries if they will last long enough until you are awake when the stores are open again.
Vitamin D deficiency is also common among people with free running N24 due to spending half our lives in a nocturnal phases. On top of all that, there's often a social stigma around sleep disorders; people who sleep in late or are not able to adhere to regular schedules are thought of as lazy, and having a sleep disorder is seen as a personal failure; they think that if you tried harder to go to sleep and wake up on time, or if you had better sleep hygiene, you wouldn't have these issues.

Wow, that all sounds like it sucks, are there any cures?

Not any that work consistently for everyone. Some people with N24 are able to entrain themselves to a 24 hour schedule with light therapy and melatonin treatment. I've also heard of the method of microdosing melatonin a few hours before the target sleep time to try and simulate when the brain of people without N24 starts to release natural melatonin.

Not all of these methods work for everyone though; personally I've tried all of these methods and sadly did not have any luck with adhering to a 24 hour schedule. Basic sleep hygiene advice also does not help with N24; It's not just poor sleeping habits and can not be managed through willpower alone. Yes, I've tried avoiding looking at screens before bed. Yes, I've tried blue light filters. Yes, I've tried exercise before bed to tire myself out. They do not work for N24.
That's all I can think of to say on N24 at the moment. I hope I've done a decent enough job of explaining this disability and the many ways it messes up the day to day lives of the people who suffer from it. If anyone has any questions about N24 feel free to ask, I'm happy to answer them to the best of my ability (Or if anyone else who has N24 has corrections also let me know, I suffer from it but I am not a medical professional so I can only really speak from my personal experience with it).

@rubyrubedo if you're someone who truly does have an entirely flexible schedule and don't have relationships that you need to tend to,

Is it better to freerun N24 or not to freerun it?

@espressopancake if you don't have to conform to a 24 hour schedule for work / relationships etc. it definitely seems preferable to me to just free run. Its still inconvenient being out of sync with everyone else, but its preferable to the sleep deprivation that comes with the alternative.
@rubyrubedo oh hey, I also have non-24! thanks for the thread. laying down for a 4pm nap right now, lol.
almost failed college because of sleep issues. I scrape by with work from home and a biphasic schedule. usually 3 and 4 hour periods. when I get the chance to free-run it is so nice.
I've also gotten good at waking up quickly to do time sensitive work, then sleeping again.
I tried melatonin and light therapy and was able to wake up every day at the same time for a few months. it was so weird, people live like this? I didn't know what to do with myself in the mornings.
unfortunately, the melatonin worsened migraines for me. once I get through some other health issues causing the migraines, maybe I can try it again.
I worry about sleep deprivation causing health problems, kinda like shift work disorder.