HKI've been using Qubes OS for over a month now 
for everyday use, and honestly, I don't regret a thing.
It's been nine months since I left Windows and stopped relying heavily on Google and Microsoft, and I never imagined I would end up using Qubes OS, but since I started using it, I've seen more benefits than drawbacks.
For example, compartmentalizing my emails for different uses, school uses among others that I cannot mention due to the word limit.
I use Qubes BTW!!