Most of the roguelikes that I really enjoy had unlocks that made the game harder, not easier. At best, the unlocks offer new builds, making the game easier in one respect but harder in others, giving you a new angle on things.

But then again, most of the ones I play are puzzle/strategy/deckbuilder type games. Kind of a genre of its own these days. (FTL, Slay the Spire, Cultist Simulator, Balatro, etc)