Sidherian#C0VIDisnotover #maskforyourlife #cleantheair
While involved in a discussion on another platform about people forgetting COVID infections & rewriting what occurred emergency phase of pandemic I segued into toxoplasmosis (as you do) so came upon this article.
There was new to me infor about how toxo impacts its host. “Toxoplasma has managed to keep body's immune response to it low enough to ensure that it can still thrive in its human hosts, but high enough that those who are infected can live a healthy life as one giant incubator.”
And now scientists have figured out how.
"The parasite rewires the host's inflammatory response," says Matthew Bowler from the European Molecular Biology Laboratory. "It completely subverts the chain reaction that would normally trigger our body's defences."
"The parasite rewires the host's inflammatory response," says Matthew Bowler from the European Molecular Biology Laboratory. "It completely subverts the chain reaction that would normally trigger our body's defences."
Under normal circumstances, when cells in your body detect a parasite, a series of molecular signals will activate a protein called p38α, prompting it to move into the cells' nuclei. Here, it activates the genes that trigger an inflammatory response to eliminate the pathogen.
Interestingly, rather than simply blocking those signals, Toxoplasma gets its way by doing the exact opposite: Bowler and his team found that the parasite actually kickstarts the human inflammatory response, and proceeds to manipulate it according to its own needs. “
Which reminded me of this paper.
Pattern recognition served me very well in my career but there are times I wish it would switch off.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8667538/
Pattern recognition served me very well in my career but there are times I wish it would switch off.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8667538/
Host Manipulation Mechanisms of SARS-CoV-2
Viruses are the simplest of pathogens, but possess sophisticated molecular mechanisms to manipulate host behavior, frequently utilizing molecular mimicry. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to bind to the ...
Gif's Artidote@Sidherian that reminds me of my narcissistic ex-partner and the current physical & mental state i am in!