Take a number
It’s true, any time you have been slightly inconvenienced in life it was not mere coincidence but rather the targeted action of malicious wage workers against you specifically because they’re definitely that invested in your life.
That was the joke presented in the meme, yes.
Yes and I’m saying maybe instead of coddling the modern sense of cosmic self-importance by acceptance through jest, we should instead maybe tell people to like, grow up?
I really don’t see your argument here. The humor in the comic is based entirely on the subversion of expectation. Specifically the implicit understanding that these kinds of minor inconveniences are not the product of intent (malicious or otherwise).
I disagree, the humor in the comic is indulging out irrational feelings that things happen to us as a matter of cosmic consequence. This wouldn’t exist if we didn’t have a stupid internal voice that said to us “they’re doing this to you.”

instead of coddling the modern sense of cosmic self-importance by acceptance through jest

(anyone needing a translation of this admittedly fucking awesome sentence:)
“instead of normalising our own sense of entitlement”

Lol, yes that’s much more succinct, thank you
consign your trepidations to their newly fortified retainers, my auspicious accomplice!
I think they sent you the wrong sleep-hypno tapes…
Forbearance is the watchword, that triumvirate of twinkies merely overwhelmed my resolve!
I wouldn’t call this a meme but sure.