motivation

I’m not sure it’s that simple.

All of these except Minecraft have perpetual funding and labour issues, especially for the less sexy parts.

You’re not going to staff a pharmaceutical factory with volunteers.

BioHacking with local made open source pharma is already a thing.
And is that actually achieving reliable quality and traceability? Not that mass-market pharmaceuticals are perfect, but I don’t remember hearing that many scandals about actual contamination/mismanufacturing (as opposed to testing/development failures like Thalidomide).