𝕯𝖔𝖔𝖒𝖘𝖈𝖗𝖔𝖑𝖑™🧬💉⏳ Scientists in Beijing used CRISPR to nail down over 100 genes that push cells into old age. One called KAT7 speeds senescence like a bad cop on the beat. Knock it out and cells act young again. In mice, the tweak cut decay and stretched life. Human trials may be next. #AntiAgingBreakthrough https://medicalxpress.com/news/2021-01-scientists-gene-therapy-strategy-aging.html
Scientists develop new gene therapy strategy to delay aging
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated genes, the identity and roles of additional genes involved in the regulation of human cellular aging remain to be elucidated. Yet, there is a lack of systematic investigation on the intervention of these genes to treat aging and aging-related diseases.