"You should at most select 2000 Mails at once". That part within one of the docs pages of #Thunderbird kinda (but not really) explains why it starts to behave like shit when you try to do any operation on a large amount of items. Like not move any of them at all, or that action getting canceled as soon as it decides to look for new messages again. Or just freeze the entire UI.
Anyone have a recommendation for a mailclient that can handle being on large mailinglists? e.g. 10-100x that amount?