@sinabhfuil Many human pregnancies don't go to term, i.e. miscarriage. It was know that some are due to large genetic mutations. This study shows that many others are due to small but deleterious (bad for health) mutations, many which are new (the mutation happened in the egg or sperm).
The relevance to human evolution is that mutations which are deleterious are still eliminated: miscarriage due to mutation is a form of natural selection.