Victoria Stuart 🇨🇦 🏳️⚧️Antivenom neutralizes neurotoxins of 19 of world's deadliest snakes
https://www.sciencedaily.com/releases/2025/05/250502133806.htm
https://www.cell.com/cell/fulltext/S0092-8674(25)00402-7
* antibodies isolated f. hyperimmune individual self-exposed to wide variety of venoms
* result: potent, broadly cross-neutralizing antibodies against homologous snake toxins
* used to make broadly effective antivenom
* protective against black mamba, king cobra, tiger snakes in mouse trials
* path toward universal antiserum
Antivenom neutralizes the neurotoxins of 19 of the world's deadliest snakes
By using antibodies from a human donor with a self-induced hyper-immunity to snake venom, scientists have developed the most broadly effective antivenom to date, which is protective against the likes of the black mamba, king cobra, and tiger snakes in mouse trials. The antivenom combines protective antibodies and a small molecule inhibitor and opens a path toward a universal antiserum.