Thread 1/5: PREPRINT: A major milestone on #Paleoproteomics? Sciex 6600 TripleTOF analyses 99-million-year-old arthropods ๐Ÿ•ท๏ธ in amber. Study identifies proteins from #Cretaceous #Holothyrida mites & #Cornupalpatum ticks! de la Fuente et al. (2025) www.researchsquare.com/article/rs-6...
Thread 2/5: ๐Ÿ”ฌ Remarkable coverage of proteins, Elongation factor 1-alpha 71.3%. Impressive coverage of actin. If confirmed, this would mark the first fossil evidence of Holothyrida mites. We'll need to examine the PRIDE submission to verify.
Thread 3/5: ๐Ÿงช Claims about potential connections to Alpha-gal Syndrome are intriguing but speculative. Ancient DNA ๐Ÿงฌ and protein studies in amber remain controversial. Contamination is a persistent challenge that requires careful controls.
Thread 4/5: ๐Ÿฆ– Previous attempts have yielded mixed results. We found minimal protein preservation in amber-preserved #dinosaur? feathers. www.nature.com/articles/s41... While they detected amino acids, concentrations were extremely low, highlighting how challenging these analyses are.

Ancient amino acids from fossi...
Thread 5/5: ๐Ÿงฌ Amber's preservation capabilities for proteins remain debated. While promising, paleoproteomics requires exceptional methodology to distinguish genuine ancient proteins from contamination. Let's wait for peer review and independent verification. #paleoproteomics #scienceskepticism ๐Ÿ™‚