@Bp103 Though I haven't tried it, it has a Lua scripting interface (not sure what the API exposes), and I suppose you could get access to the audio signal if you created a custom plugin (e.g. LADSPA or VST).
I guess that's not a very interactive way of scripting and DSPing though?
@borememore I guess my consolation prize was figuring out how to mess with renoise so much that I could turn the sidechain effects into a standalone synth by turning the DC offset on and off really fast.
I don't have any samples or vst loaded in this one.