A whopping (~90%) reduction of progression to Type 2 diabetes with tirzepatide (GLP-1 drug, dual receptor) vs placebo in a randomized trial of >2,500 participants with obesity, absolute reduction of 10/100 treated
https://www.nejm.org/doi/full/10.1056/NEJMoa2410819
https://www.nejm.org/doi/full/10.1056/NEJMoa2410819