In his defense playing alone in a world in habited by other players even if he chooses to not talk is less lonely than a single player game where you have no options to talk to others in game.
They are both “NPCs” that neither can interact meaningfully with in the end, so what difference would it actually make?

interact meaningfully

Depends on the game. Just because verbal / written communication is turned off doesn’t mean there isn’t meaningful interaction in the game.

Other than atmospheric games like Journey which already don’t have that, do you have any other examples of how they can interact and help you without talking, trading, or being able to do anything else than walk and crouch?

Anyone who has that stuff on and notices the person is mute/deaf settings is gonna move on and ignore you themselves.

It doesn’t make the experience better or even keep it the same. It will only make it worse. The meme also says/implies all interactive settings are toggled off. So no trading, no pings (which usually don’t exist in games with chat as well), no anything else than crouch and walk.

Okay so have you ever played Minecraft?