Anestis Tsakiridis

The finalised version of our m/s on the role of Notch signalling in hPSC-derived NMPs is now out: https://journals.biologists.com/dev/article/151/3/dev202098/343013/Notch-signalling-influences-cell-fate-decisions

many thanks to
@Dev_journal for including our story in the research highlights of their February issue: https://journals.biologists.com/dev/article/151/3/e151_e0302/343046/NMPs-need-Notch

Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors

Highlighted Article: Notch signalling is a crucial regulator of the induction and differentiation of posteriorly located neuromesodermal axial progenitors, the precursors of the neural and mesodermal components of the amniote embryonic body trunk.

The Company of Biologists
Feb 12, 2024 at 1:33pmWeb
Show threadAnestis TsakiridisFeb 12, 2024
Fay and I are also discussing the background of this work in the related @Dev_journal "The people behind the papers" feature: https://journals.biologists.com/dev/article/151/3/dev202709/343014/The-people-behind-the-papers-Fay-Cooper-and
The people behind the papers – Fay Cooper and Anestis Tsakiridis

Neuromesodermal progenitor (NMPs) give rise to neural and mesodermal tissues during axis elongation. In their study, Fay Cooper, Anestis Tsakiridis and colleagues reveal the role of Notch signalling in NMP differentiation and its role in Hox gene expression. To learn more about their work, we spoke to first and co-corresponding author, Fay Cooper, and to co-corresponding author Anestis Tsakiridis, Group Leader at the University of Sheffield, UK.

The Company of Biologists