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sevish I use #
SuperCollider, which has built-in support for scales and tunings via the Scale class and Tuning class. The #
TuningLib add-on (which, disclaimer: I co-wrote) has some additional support for key changes, opening scala files and some odds and sods.
I also very occasionally use the Java Just Intonation Calculator which is not brilliant, but I was/(am?) the maintainer for it, so I know how to use it. #
JJICalc I don't tend to mess around with floating point MIDI, but it should be possible, I think? My MIDI-> CV converter is hella old, so only deals with integer note values. I keep meaning to do something with an arduino instead, but never get around to it.
This probably isn't terribly helpful. What kind of music do you do?