Denis - The COVID info guy -

Exercise intolerance is one symptom associated with long COVID. A new study helps explain its cause.

“We found that despite the fact that the heart was pumping oxygenated blood that the lungs were providing adequate amounts of oxygen for, the extraction of oxygen by the body’s tissues was compromised in patients who had symptoms of exercise intolerance after COVID"

#COVID19 #LongCOVID #ExerciseIntolerance @auscovid19

Source: https://news.yale.edu/2023/12/19/study-helps-explain-post-covid-exercise-intolerance

Study helps explain post-COVID exercise intolerance

Exercise intolerance is one symptom associated with long COVID. A new study helps explain its cause.

YaleNews
Dec 19, 2023 at 10:09pmWeb
Show threadViolet MadderDec 20, 2023

@DenisCOVIDinfoguy @auscovid19

The problem is in the mitochondria, isn't it? The oxygen is there but the energy isn't getting generated.

Show threadGS LakesDec 20, 2023
@violetmadder @DenisCOVIDinfoguy @auscovid19 I found the mitochondrial efficiency boosting supplement PQQ helped with my PEM from COVID
Show threadkbDec 20, 2023
@gslakes @violetmadder @DenisCOVIDinfoguy @auscovid19 PQQ?
Show threadGS LakesDec 20, 2023

@donkeyblam Its purpose is explained here:

https://www.healthrising.org/blog/2020/12/18/5mitochondria-coq10-d-ribose-fibromyalgia-chronic-fatigue-syndrome/

I also take it with CoQ10, which seems to be needed alongside PQQ to help deal with vascular damage i.e. helping get fuel to and remove waste from an energy production cycle working more efficiently again.

Show threadViolet MadderDec 20, 2023

@gslakes @donkeyblam

Ooh, thanks!

Show threadCassandraZeroCovidDec 20, 2023

@DenisCOVIDinfoguy @auscovid19
☝️
"Some patients have been told that their symptoms are a result of deconditioning, or decline from lack of physical activity, and that reconditioning alone would address the intolerance.

“Our findings contradict that hypothesis, and instead support the idea that there is a clear physiologic abnormality underpinning the symptoms experienced by our patients,” said Kahn."

Show threadNicole ParsonsDec 20, 2023

@DenisCOVIDinfoguy @auscovid19

Damaged mitochondria?
https://www.science.org/doi/10.1126/scitranslmed.abq1533

https://www.nih.gov/news-events/nih-research-matters/sars-cov-2-can-cause-lasting-damage-cells-energy-production

https://www.cidrap.umn.edu/covid-19/sars-cov-2-can-damage-mitochondrion-heart-other-organs-study-finds

https://www.chop.edu/news/researchers-find-covid-19-causes-mitochondrial-dysfunction-heart-and-other-organs

https://www.everydayhealth.com/coronavirus/mitochondrial-dysfunction-may-be-to-blame-in-long-covid-19/