AdGuard (system wide), PiHole, inbuilt adblockers are still there and won’t be affected by this. Who cares.

Adguard and pihole rely on DNS redirects - googs has already implemented “secure DNS” for Chrome in Android, which circumvents network level/local DNS by connecting to a Google owned DNS, serving content using those listings instead.

They’ll likely bring this to all flavors of Chrome.

Yes, one should use Firefox. Yes that could also avoid the android problem, but also no, because Google forces chrome at weird times (eg, some apps will load a minimal web viewer for hyperlinks links, without leaving the app - sometimes apps don’t respect the default browser setting and instead just use chrome.

🤷