The Arctic permafrost is 1,000 years old. As it thaws, scientists worry what it might unleash

https://lemmy.nz/post/3590726

The Arctic permafrost is 1,000 years old. As it thaws, scientists worry what it might unleash - Lemmy NZ

Saw that movie at a drive-in when it was released and it freaked the shit out of me.
The Last Winter

In the Arctic region of Northern Alaska, an oil company's advance team struggles to establish a drilling base that will forever alter the pristine land. After one team member is found dead, a disorientation slowly claims the sanity of the others as each of them succumbs to a mysterious fear.

The Movie Database
Ennio Morricone soundtrack intensifies
Come on xenomorph nests!
I’d be down for that. I dunno why people hate on the xenomorph babies so much though. They just want a kiss.
Can’t wait for those old plagues to make a come back.
Most of those should be bacteria, not a virus. I would speculate that they would be much easier to treat with common antibiotics. After all, they haven’t had time to adapt and become drug resistant… Yet.
I ain’t afraid of old plagues. A 10,000 year old bacterium infecting a human is the equivalent of someone bringing a spear to a gunfight

Micro-evolution is fucking wild.

In the linked experiment, it takes bacteria 11 days to evolve resistance to 1000x the concentration of antibiotics normally needed to kill it. This is basically the concern with overuse of antibiotics in healthcare, hygiene products, and livestock - that 0.001% of bacteria your soap doesn’t kill is basically the Superman of bacteria, and you just killed all its competition, leaving it free to replicate into its own little army.

A high enough dosage of literally anything is toxic / eventually fatal for humans, so we can’t just keep upping the concentration of antibiotic medication. There’s even a term for it - “post-antibiotic era”, which we’re already knee-deep into.

Anyway, yeah most ancient microbes would be absolutely destroyed by all the modern natural and artificial means that have developed to kill it… the catch being that if the microbe is old enough, things haven’t developed to kill it, so the current state of our immune systems and medical tech could amount to an all-you-can-eat-buffet for something that didn’t develop adjacent to us. Combine that with a few weeks of petri-dish-experiment of ancient microbe incubating in some immunocompromised old man who decides he’s tired of staying home sick and wants to go out christmas shopping for his family… and now we have a problem.

Watch antibiotic resistance evolve | Science News

YouTube

0.001% of bacteria your soap doesn’t kill is basically the Superman of bacteria

I have jokingly said that for years about the marketing on soaps and nobody believed me. :)

Micro-evolution is absolutely crazy though. I started learning about that with fungi; mycelium specifically. Those little things can shift their genetics lightning fast. If they are exposed to different nutrient sources or growing conditions, life… uh… finds a way. There is a debate that is going on right now about the whole naming convention of fungi being broken since fruit characteristics aren’t telling a complete enough picture. While most strains of, say, oyster mushrooms can produce the exact same fruit they might have wildly different genetic markers while still behaving like they are from the same strain.

I think this was discovered when mycologists tried to import some mycelium into New Zealand. Different batches of mycelium were comming from the same exact strain and lineage but when it was tested for import, the genetics were too far off to match to a “legally importable” strain.

Genetic “drift” is well known. After duplicating the same strain over a number of years from petri dish to petri dish, the mycelium just adapts to a cheap and easy agar food source and its fruiting tendencies may suffer as a result. What is new, is how fast it can actually happen in the wild without it going through the genetic lottery of spore combination.

(Disclaimer: I am horrendously tired right now and I tend to jumble factoids in this state. Slap me if I got something horribly wrong.)

We saw it in real time, accidentally, in a microbiology class I took.

Lab final was basically “swab this mystery petri dish, run some tests, and tell me what it is”. So, start running different stains and indicator tests, result was eventually pretty clearly S. Aurius. Except it wasn’t. The thing that gave it away was a manitol digestion test, which S. Aurius pops positive for, but the other strain of S. ___ we tested for pop negative.

Everyone’s manitol test was positive, but the correct answer should have been S. Epidermidis.

Prof thought the test sample was contaminated, so he did an isolation swab on his own time… still a pure sample of S. Epidermidis, it just evolved under our nose to digest manitol and fucked everyone’s lab result.

He had to change everyone’s grade. :D

You mean “ancient plagues”. It’s scarier that way, because of the ‘implications’
Are these women in danger?
Want to make it scarier, say “Biblical plagues”. Gotta get those evangelicals really riled up.
I hope the end of this post title is meant to be “good dogs who have been tied up too long.”
I hope it releases the end of capitalism
It will, but something tells me it won’t be the way we would hope.

Unfrozen Caveman Lawyer

We have to be subjected to another run of that Cavemen show that GEICO did, based on that commercial.
I’m pretty tired. I welcome the end of the world.
The methane and CO2 are pretty bad, too.
Stargate already covered this one; we all die from newly exposed bacteria/disease that is was previously locked away in ice
The Talos Principle, as well.
How High We Go In The Dark
Nah. Not worried about microorganisms. The way our immune system works is that it stores the “fingerprint” of pathogenic bacteria and viruses and this data is passed down to our progeny. So, we already have built in immunity to 1000 year old pathogens. In addition, vaccination has also “side loaded” many pathogen’s fingerprints.
That… doesn’t make any sense. If what you said was true, every baby alive would magically have immunity to everything any human has faced ever and would never get sick. Kids are CONSTANTLY sick.

It’s actually better than OP said. We have a T cell for every antigen. Period. Even the ones that nobody has ever encountered. That’s because an antigen is a combination and a T cell for every combination is randomly produced by the immune system (if it does not harm the host).

The caveat is that it takes a while for the T cell of an unknown antigen to be produced, enough time for the sickness to appear and even become critical.

Sounds better than having trump as president again. I’ll welcome death.
Can’t wait to all die out and leave behind an playing god to make another AI that plays human to get tetrominoes and stars.
Literal metric fucktons of ancient dog poop.