The University of Pennsylvania is acting proud of Katalin Karikó now that she's won a Nobel. But they kicked her out of her research assistant professor job when she insisted on doing the work that won her that prize:

"She recalls spending one Christmas and New Year’s Eve conducting experiments and writing grant applications. But many other scientists were turning away from the field, and her bosses at UPenn felt mRNA had shown itself to be impractical and she was wasting her time. They issued an ultimatum: if she wanted to continue working with mRNA she would lose her prestigious faculty position, and face a substantial pay cut.

”It was particularly horrible as that same week, I had just been diagnosed with cancer,” said Karikó. “I was facing two operations, and my husband, who had gone back to Hungary to pick up his green card, had got stranded there because of some visa issue, meaning he couldn’t come back for six months. I was really struggling, and then they told me this."

"While undergoing surgery, Karikó assessed her options. She decided to stay, accept the humiliation of being demoted, and continue to doggedly pursue the problem. This led to a chance meeting which would both change the course of her career, and that of science."

Elsewhere she recalled:

“I thought of going somewhere else, or doing something else. I also thought maybe I’m not good enough, not smart enough."

She's now an adjunct in UPenn's neurosurgery department. Will they fast-track her for tenure now that she has a Nobel, or just live with the shame?

Both quotes here come from interesting stories. The first is from here:

https://www.wired.co.uk/article/mrna-coronavirus-vaccine-pfizer-biontech

The second is from here:

https://billypenn.com/2020/12/29/university-pennsylvania-covid-vaccine-mrna-kariko-demoted-biontech-pfizer/

How mRNA went from a scientific backwater to a pandemic crusher

For decades, Katalin Karikó's work into mRNA therapeutics was overlooked by her colleagues. Now it's at the heart of the two leading coronavirus vaccines

WIRED UK
@johncarlosbaez I'm not too familiar with the way things work in academia, but how often do demotions happen generally?
@watchie - People can fail to get tenure, but I've never heard of them being "demoted" to adjuncts; I believe that would be against the rules at my university (the University of California). So I would like to understand in more detail what happened here.

@johncarlosbaez Interesting, I figured it would be well known in academic circles. If you find anything I'd love to hear about it.

Seems like they were less than gracious to her, even if demotion is a common thing; but if it isn't that's even worse.

@johncarlosbaez @watchie Why the focus on being “demoted”? If you support the notion of people being denied tenure as part of that career path, surely you can imagine a scenario where someone would want to stay at an institution for any number of reasons: stay near family, tuition benefit, etc. If tenure review decides that someone isn’t successful enough at publishing/raising money, is the university doing something wrong letting them stay on in another capacity?
@johncarlosbaez have also never heard of it. I mean, sometimes very elderly tenured faculty get put into tiny offices or whatever to "encourage" them to retire, but demotion? I'd think it was very much against the rules. or even messing with somebody's research plan! maybe she had a weird niche appointment originally.
@acm_redfox - it turns out that article was written by someone who doesn't quite know academia. I've now learned a few details and they seem a bit different: she was a research assistant professor paid for by soft money, apparently from other people's grants, and when her research seemed to not be going anywhere those people said she should work on something else or she'd have get a job as an adjunct. That's my impression, anyway.