@lexolf
Ah, I never use bookmark sidebar. Adding Shift brings up the "Library" window.
The full pref name is "dom.keyboardevent.keypress.hack.use_legacy_keycode_and_charcode" -- "legacy" is the key word there. Early web behavior was underspecified, and relevant to this case there were slight differences in how browsers sent key events. Around 2018 or so Firefox made changes to comply with the W3C standard. It took a while for sites to stop using "if Firefox do XXX" key handling instead of the standard, so that pref was the escape valve. Some sites to this day still only work with the legacy Firefox behavior.
It's not that Firefox is "stealing" the Ctrl+B, it's that the site didn't recognize it and then the uncaptured event fell through to the browser.
What I don't understand is how sites as popular as live.com and sharepoint.com wouldn't be in our exception list if they're getting it wrong. Do you have any customizations that might make your browser look really old to those sites?