Top US health officials recommend that marijuana be shifted to a less restrictive category of drugs: Bloomberg
@GottaLaff No shit. Use Canada as a starting point.

@GottaLaff

Cannabis is intrinsically not a drug, it's a plant and it shouldn't be scheduled at all.

@mycotropic Alcohol is plant based too. It's a drug. So not sure that's the thing to base it on.

But you're right about the rest.

@mycotropic @GottaLaff

All in favor of legal THC. Can't be against that and not also against alcohol. It's both or neither.

HOWEVER:

Basically every drug we have was a plant first. Cannabis today is VERY different from what grew naturally. The THC level is 20x or more what it was 30 years ago, and the ratio of THC to CBD can be as much as 50:1 where naturally growing stuff was 1:1. In fact, that ratio is why today's strains can actually be dangerous when that didn't used to be the case.

@FirefighterGeek @GottaLaff
I'm an epidemiologist and I've done state funded cannabis research, I'm also on the scientific advisory board for HB21-1317 in #Colorado. The problem with your statement is that there is almost no research directly testing outcomes for high concentration cannabis. Here's the page, report and dashboard of all of the research;
https://coloradosph.cuanschutz.edu/research-and-practice/practice/cannabis-research/resources
Resources | Cannabis Research & Policy Project | Colorado School of Public Health

@mycotropic @GottaLaff I'm not sure I was making any particular commitments in that regard. We do have plenty of data showing rates of problems related to it have gone up, that's worth a warning.

As I understand it, CO has an excellent program for both CBD and THC products requiring a QR code leading to batch level tests showing both levels on products being sold. Is that true (I'm not in CO)? I'd be more inclined to try CBD for some things if I had access to that data for products here.

@FirefighterGeek @GottaLaff we do and it's effective to a certain extent, if you test positive for a contaminant it kills the whole batch, immediate discard and that's hundreds of thousands of dollars if it's a big batch so the incentive is to carefully pick your submitted sample. Also researchers are not able to pull concentration data directly from the testing data, it's actually a crime for that department to release testing data for #reasons.
We have good and less good actors!
@mycotropic @GottaLaff still sounds like a good program. I've had some minor nerve related stuff that could (maybe) be a good target for future CBD based treatments but I wouldn't bother trying it here because what's in the bottle could just as easily be Moroccan hair oil as anything else. No real way to know at the retail level.
@FirefighterGeek @GottaLaff
That's true and Colorado did a test sample from a bunch of gas stations I believe and found exactly no.CBD oil in a bunch of labeled products. The stuff out of Israel looking at CBD for TBI recovery looks really interesting, there's a time window but they've published papers showing a signalling effect on inflammatory cells localized in recently damaged neural tissue.
@mycotropic @GottaLaff Yeah, my understanding (such as it is) is that they've found receptors for it that would match the molecule all over but mostly on the nervous system. The theories I've read are that it helps healing the sheathing of the nerves. There was also a study that showed dramatic and sometimes permanent benefits in early treatment of patients developing schizophrenia.
@FirefighterGeek @GottaLaff I'm not on the neural side of things but I think the Israeli work showed that CBD bound neurons at the interface and modulated inflammatory infiltration of cells which let newly damaged nerves heal themselves or something similar. If you read PubMed I'll dig up the reference if I can find it.
@mycotropic @GottaLaff I'm strictly a lay-person. I read a lot, maybe the occasional journal article, mostly intelligent but general press stuff. I don't have the background for interpreting the more formal papers. Thanks though.