I’d recommend against using pipewire over pulseaudio, and in turn eassyeffects rather than pulseeffects. Pipewire is a much cleaner implementation, way less buggy, has a wider support. As far as I’m aware pretty much every major distro ha smigrated to pipewire aleady.

This is going 0 to 100 quickly, but I would personally run your mic into a DAW and process it with effects there. It’s what DAWs are designed to do. Use its output as an audio input for your applications.