Q453
A young adult presents to the ER with a severe nosebleed - he says he often gets bad nosebleeds, especially at night. On examination, a few small red lesions are noted on his tongue and face. He mentions that his father had “some kind of blood vessel problem in his lungs.” What diagnosis is most likely?
Cowden syndrome
0%
Hemophilia
0%
Hereditary hemorrhagic telangiectasia
66.7%
von Willebrand disease
33.3%
Poll ended at .
Hereditary hemorrhagic telangiectasia: genetics and molecular diagnostics in a new era - PubMed

Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by telangiectases and arteriovenous malformations (AVMs) in particular locations described in consensus clinical diagnostic criteria published in 2000. Two genes in the transforming growth factor-beta (TGF-β) signaling …

PubMed