How do you make large cuts of pork or beef that fall apart on the plate using only an oven?

https://beehaw.org/post/687046

How do you make large cuts of pork or beef that fall apart on the plate using only an oven? - Beehaw

I’m not talking “you don’t need a knife” level here, I’m looking for, “you need a spoon to finish the last bits” level of falling apart. What are your specific techniques and tricks for different cuts? Also, if you know a great Tennessee style dry rub I really want to know about it please.

Low and slow is my advice too - but also IME there's something magical that happens when you use creamy soups as a starter with your meats. I spent years trying to make something healthier than my mom's roast beef recipe, which is basically cream of mushroom soup and onion soup mix plus a roast, but nothing I did could make it fall apart and stay moist like hers. I settled on using real onions in place of the onion soup mix which helps lower the salt content a bit but my family often asks me to just make it like my mom did.