Just published in Conservation Biology: We ask how the new 1st US Natl Nature Assessment can become not only an information resource but also a vehicle for broader engagement of researchers, practitioners, and society with strategies for reversing biodiversity loss. The NNA should draw lessons from the new global biodiversity framework in part by including and promoting application of key biodiversity indicators developed as part of the new global monitoring framework. https://conbio.onlinelibrary.wiley.com/doi/10.1111/cobi.14075