Our Endemic COVID Future Is Probably Not What You Think--Why More Action Is Necessary Now (A long 🧵 ):

Many think we're already “post-COVID.” We're not, but it does beg the question of what the future has in store for us. If we ignore how tired everyone is of #COVID19 and instead explore the latest data and studies, we may see that we've not yet fully understood or adjusted to our COVID future. We've gone back to “old normal” when a “new normal” is necessary.

WHY WE'RE NOT POST-COVID

No, the pandemic is not over. The World Health Organization says we're still in a pandemic. WHO declared the public health emergency on 30 January 2020 and a pandemic on 11 March 2020, and it's the entity that gets to decide it's over--not you, me, or President Biden. Days ago, WHO held a meeting to discuss COVID, and it determined the pandemic remains a public health emergency of international concern.
https://www.euronews.com/next/2023/01/30/who-to-keep-highest-alert-over-covid-as-public-health-emergency-of-international-concern

WHO keeps highest alert over COVID three years on

Three years after COVID was first called a global health emergency, the World Health Organization (WHO) has decided to keep its highest alert over the disease.

euronews
Some claim COVID is endemic, but this is not true. It will be endemic, eventually, but it isn't yet. For a disease to be endemic, it must be consistently present and cause a steady, predictable number of people to get sick. This is far from the case with COVID-19 right now. In the last three months, the US has seen two variants become predominant in rapid succession, and these were variants scientists had only just discovered four months earlier. That is not predictable. https://covid.cdc.gov/covid-data-tracker/#variant-proportions
COVID Data Tracker

CDC’s home for COVID-19 data. Visualizations, graphs, and data in one easy-to-use website.

Centers for Disease Control and Prevention
The US has also had three surges of hospitalizations in the past year. Unlike the flu, which has a predictable annual season, COVID is not yet steady.
https://covid.cdc.gov/covid-data-tracker/#new-hospital-admissions
COVID Data Tracker

CDC’s home for COVID-19 data. Visualizations, graphs, and data in one easy-to-use website.

Centers for Disease Control and Prevention
The US has not had a significant surge in COVID death in a year, although it continues to have a troubling level of COVID fatalities, losing around 3,500 people a week. But, we may yet see another significant wave of deaths. Other nations, like Japan and Sweden, have experienced their first- or second-highest levels of #COVID19 deaths of the pandemic in the past month or so.
https://ourworldindata.org/explorers/coronavirus-data-explorer?zoomToSelection=true&time=2020-03-01..latest&facet=none&pickerSort=desc&pickerMetric=new_deaths_smoothed_per_million&Metric=Confirmed+deaths&Interval=7-day+rolling+average&Relative+to+Population=true&Color+by+test+positivity=false&country=SWE~JPN~NOR~AUS~HKG~FIN
COVID-19 Data Explorer

Explore global data on COVID-19.

Our World in Data
None of this suggests that we've yet reached a stable place with COVID. Experts warn new variants could soon cause yet another surge of illness and hospitalization.
https://today.tamu.edu/2023/01/30/what-you-need-to-know-about-xbb-1-5-covids-latest-variant/
What You Need To Know About XBB.1.5, COVID’s Latest Variant

Texas A&M experts explain how the subvariant of Omicron has become the dominant strain in parts of the U.S.

Texas A&M Today

BUT WHAT MIGHT OUR COVID-ENDEMIC FUTURE LOOK LIKE?

Too many folks repeat the discredited idea that COVID is “just the flu.” It's led to folks thinking that COVID will be a minor inconvenience for the vast majority of the public on some annual basis. First of all, "just another flu" would be nothing to take lightly. The flu hospitalizes between 250,000 to 600,000 people annually in the US most years, and it kills between 20,000 to 60,000 people.
https://en.wikipedia.org/wiki/United_States_influenza_statistics_by_flu_season

United States influenza statistics by flu season - Wikipedia

But #COVID19 is not "just the flu.” A new study suggests that our endemic future is one with risks that demand much more public, not just individual, action. It concludes that “individuals seeking to opt out of adverse outcomes upon SARS-CoV-2 infection will find it challenging to do so, as large reductions in contact rate are required to reduce the risk of infection.”
https://www.medrxiv.org/content/10.1101/2023.01.22.23284884v1.full

Some specific findings from this study include:

There's little individuals can do to protect themselves short of enormous sacrifice if we don't implement public health solutions. Vaccinated people wishing to reduce their frequency of infection by half will need to reduce their contact rate 10-fold. People who only reduce their contact rate by half will “experience infections rates only marginally less” than those who have a median level of contacts with others.

People who are vaccinated and not taking measures to reduce their contact rate can expect to spend an average of 6 days a year acutely sick with COVID-19 and be infected 1.4x annually. That's a #COVID19 infection every 8.5 months on average. Now is a good time to remind the "just the flu" folks that the average American gets the flu once every 10 years or so.

https://www.cdc.gov/flu/about/keyfacts.htm

Key Facts About Influenza (Flu)

Learn key facts about influenza to fight against flu.

Centers for Disease Control and Prevention
The study estimates that 2% of vaccinated individuals who have a median contact rate will experience long COVID so severe that it impacts their employment. Sounds small, but think of 1 of every 50 people being that disabled. That is a frightening situation.

Not only isn't COVID like the flu in terms of its evolution, transmission and frequency, we're also learning #COVID19 infections are likely much more dangerous to long-term health. To focus on just three out of 150 studies demonstrating the ways COVID can damage hearts, brains, immune systems, reproductive organs, kidneys and organs:

One study found that people who had COVID have a 43% higher risk of developing auto-immune issues.
https://www.medrxiv.org/content/10.1101/2023.01.25.23285014v1

Another study found those who had #COVID19 have a 60% greater risk of myocardial infarction and 39% higher risk of stroke.
https://www.mdpi.com/2075-4418/13/3/491
Long COVID Syndrome and Cardiovascular Manifestations: A Systematic Review and Meta-Analysis

(1) Background: Long COVID syndrome is a significant cause of morbidity in COVID-19 patients who remain symptomatic with varied clinical presentations beyond three weeks. Furthermore, the relevance of considering cardiovascular outcomes in post-COVID-19 syndrome is important in the current COVID-19 pandemic; (2) Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for this systematic review and meta-analysis. Systematic searches were conducted from multiple databases without language restrictions until October 8, 2022, to find studies evaluating cardiovascular outcomes such as arrhythmias, myocardium and pericardium diseases, coronary vessel disease, and thromboembolic disorders in post-COVID cases. The pooled odds ratio (OR), and standard mean difference (SMD) with their corresponding 95% confidence intervals (CI) were computed to find the association; (3) Results: Altogether, seven studies with a total of 8,126,462 (cases: 1,321,305; controls: 6,805,157) participants were included in the meta-analysis. Pooled odds ratios of cardiovascular outcomes were significantly higher in post-COVID cases (OR > 1, p < 0.05) than in controls. However, the mortality (OR: 4.76, p = 0.13), and heart rate variability (SMD: −0.06, p = 0.91) between cases and controls were not statistically significant; (4) Conclusions: Significant cardiovascular sequelae in long COVID syndrome highlight the importance of careful cardiac monitoring of COVID-19 patients in the post-COVID phase to address cardiovascular complications as soon as possible; larger-scale prospective studies are required for accurate estimation.

MDPI

And another study uncovered the much greater risk of cognitive impairment in people following a COVID infection.

https://www.sciencedirect.com/science/article/abs/pii/S0165178122005972

Doctors won't necessarily tie individual heart attacks, strokes, diabetes diagnoses and the like to past #COVID19 infections from which people have recovered. Instead, what we'd see in a population that is repeatedly infected is an increasing burden of poor health and rising excess deaths. And that is precisely what is happening. Excess deaths (which is the number of people dying above historic averages) are very high and rising in many countries.
https://ourworldindata.org/grapher/excess-mortality-p-scores-projected-baseline?country=GBR~IRL~CHE~SWE~JPN~HKG~DEU
Excess mortality: Deaths from all causes compared to projection

The percentage difference between the reported number of weekly or monthly deaths in 2020–2024 and the projected number of deaths for the same period based on previous years.

Our World in Data
Take Ireland as an example. Currently, the #COVID19 risks are lower than they've ever been since I moved here in October 2021. Our hospitalizations and positive rate of testing are the lowest they've been in 15 months. So, why do we have record levels of deaths so great that mortuaries can't keep up?
https://www.breakingnews.ie/ireland/number-of-deaths-in-recent-weeks-leading-to-funeral-delays-1425557.html
Number of deaths in recent weeks leading to funeral delays

The rise has resulted in capacity issues at Cork City Morgue, with bodies having to be stored in hospitals overnight.

BreakingNews.ie
The excess-death situation is so pressing that actuaries--the people who guide long-term decisions for pensions and insurance companies--are beginning to adjust their assumptions. Continuous Mortality Investigation says “mortality in 2022 may be indicative of future mortality… life expectancy assumptions at age 65 are likely to fall by around 6 months, equivalent to 2%… higher death rates seen in the latter part of 2022 may be indicative of future mortality.”
https://www.lcp.uk.com/media-centre/2023/02/life-expectancy-assumptions-could-fall-by-6-months-if-cmi-proposals-adopted/
Life expectancy assumptions could fall by 6 months if CMI proposals adopted

The CMI has issued its consultation to help shape the next version of its mortality projection model, which is used by the majority of pension scheme trustees and sponsors in setting their funding and accounting assumptions. The consultation focuses on how to respond to the very high mortality rates seen in England & Wales over 2022, to which the model is calibrated. 

While the typical group of COVID-minimizing, herd-immunity-hyping, mask-hating folks love to blame the vaccines for excess deaths, the evidence is substantial and in no doubt among experts that vaccines do much more good than harm. No vaccine is 100% safe, but we get vaccinated because the risks are miniscule compared to the risks of getting a deadly or disabling disease.
https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/is-the-covid19-vaccine-safe
Is the COVID-19 Vaccine Safe?

Our experts answer some frequently asked questions about vaccine safety.

Our endemic future isn't a return to 2019 norms but demands a new way of thinking of public health. If your personal risk isn't enough to encourage a change in your perception and behavior, perhaps you'll care more about the threat to the economy.
https://www.bloomberg.com/opinion/articles/2022-12-07/long-covid-is-a-threat-to-the-whole-economy?leadSource=uverify%20wall
We are seeing a historic decline in lifespans. We can wait a few more years, lose more lives to disability and death, and see how much more our lifespans decline, or we can begin to understand that #COVID19 wasn't a temporary situation for us to get past. COVID, I believe, must be recognized as a global change in the risks we face and the way we live. We need to stop pretending our 2019 normal makes sense and figure out what our 2024 normal ought to be.
https://www.forbes.com/sites/joshuacohen/2023/01/01/the-number-one-health-story-from-2022-is-the-troubling-decline-in-life-expectancy/
The Number One Health Story From 2022 Is The Troubling Decline In Life Expectancy

The biggest health story from 2022 isn’t Covid-19. It isn’t RSV or influenza, either. It isn’t cancer, diabetes, or cardiovascular disease. It’s something that encompasses all these diseases and much more. It’s the troubling decline in U.S. life expectancy.

Forbes

HOW TO RESPOND TO OUR COVID-ENDEMIC FUTURE

There is a range of things we ought to do to create the conditions for a healthier, safer future. But, none of this will work on a voluntary basis. Public health can't be left to individual choice. It's called “public” health for a reason!

If you don't believe me, let me ask you three questions:

First, are you masking on long flights? No? Then you're ignoring the guidance provided by WHO to keep you and others safe.
https://www.reuters.com/world/whoeurope-backs-travel-checks-us-given-spread-latest-omicron-variant-2023-01-10/

WHO urges travellers to wear masks as new COVID variant spreads

Countries should consider recommending that passengers wear masks on long-haul flights, given the rapid spread of the latest Omicron subvariant of COVID-19 in the United States, World Health Organization (WHO) officials said on Tuesday.

Reuters

Second, do you mask when in crowded indoor spaces? No? Then you are disregarding the latest advice WHO offers, which is masking “for anyone in a crowded, enclosed, or poorly ventilated space.”

https://www.who.int/news/item/13-01-2023-who-updates-covid-19-guidelines-on-masks--treatments-and-patient-care

WHO updates COVID-19 guidelines on masks, treatments and patient care

The update is part of a continuous process of reviewing such materials, working with guideline development groups composed of independent, international experts.

@augieray most people do not have the ability to accurately assess whether a space has "poor ventilation."
@tippenring I agree, but what's your point? I'd hope governments would implement rules for safer indoor air. In the absence of that, it seems this sort of advice is the best we can hope for.
@augieray my point is that the government undermines itself with such guidance. Advising untrained civilians to do something they are incapable of encourages the mindset that government advice is generally ridiculous, leading to people dismissing all of it out of hand without consideration.