A đź§µ on why 2023 is shaping up to be yet another dangerous new phase for the pandemic.

In the worst week of the pandemic thus far, eleven months ago, the world saw 24 million confirmed cases. China is about to enter an enormous surge after lifting most of its precautions, and experts are predicting China could see 800 million cases in the next three months:

https://www.npr.org/sections/goatsandsoda/2022/12/15/1143002538/china-appears-to-be-facing-what-could-be-the-world-s-largest-coronavirus-outbrea

COVID spreading faster than ever in China. 800 million could be infected this winter

Scientists predict China will see the largest COVID surge of the pandemic this winter, with hundreds of millions of people infected. But some experts say that it could have been even worse.

NPR
Not even counting the rest of the world (where COVID is also surging), China could see an average of 67 million cases a week over winter--almost 3x greater than the world's previous peak. (The expected death rate in China means 2023 will likely be a more deadly year for COVID around the world than 2022 has been.)

Of course, we won't see this surge in the data; China can't test or report that level of infections. And, much of the rest of the world has reduced testing and reporting. So, we'll fly largely blind through the worst part of the pandemic globally.

What we lack in data, we may make up with horror stories out of China; in fact, they're already starting, and it's only been two weeks since China eased its COVID restrictions:
https://www.businesstoday.in/latest/world/story/covid-horror-in-china-overloaded-morgues-hospitals-exhausted-crematorium-workers-357027-2022-12-20.

Covid horror in China: Overloaded morgues, hospitals & exhausted crematorium workers

Hospitals, funeral homes, and crematoriums in Beijing are reportedly struggling to keep up with the surge in deaths of late.

Business Today
And elsewhere, we'll monitor for signs of COVID rising in other ways. In the US, we'll see in the positive rate of testing, which is currently the highest it's ever been, per Walgreen's COVID-19 Index (https://www.walgreens.com/healthcare-solutions/covid-19-index) (although the CDC's data disagrees.) We'll see it in hospital admissions, which are up 50% in a month (https://covid.cdc.gov/covid-data-tracker/#new-hospital-admissions) (although still below past peaks). And we'll see it in wastewater testing, which is up 80% in the past two months (https://biobot.io/data/).
Walgreens Respiratory Index | Walgreens Healthcare Solutions

Explore the Walgreens COVID-19 Index, taking data from our stores to visualize trends and patterns in COVID-19 across the United States.

The US is already in a COVID surge, driven by new immune evasive variants. The BQ family became predominant a month ago after surpassing BA.5, and the XBB family of variants is racing up behind it. XBB.1.5 is growing phenomenally quickly, showing a 100% growth advantage over BQ.1 according to virus modelers. In New York, XBB has a head start and is already the most common variant, and hospitalizations in the state are the highest since February and rising steadily:

https://coronavirus.health.ny.gov/daily-hospitalization-summary

Daily Hospitalization Summary

New admissions and total hospitalizations, by region

Department of Health
XBB's immune evasion and growth advantage, in combination with poor bivalent booster uptake and maskless holiday travel and gatherings, suggests the rest of the nation will see a renewed surge well into January. And if new variants continue to rise, it might be more difficult to knock this surge down than it was past waves of COVID.

We may not beat last holiday's COVID patient totals, but we don't need to because hospitals are also filling up with patients with RSV, flu, Strep A and other illnesses. Hospitals are the fullest they've been since the start of the pandemic dealing with all of these patients. It won't take much of a COVID surge to max out capacity in many hospitals. Parents are already struggling to find hospital beds for sick kids in parts of the US:

https://www.washingtonpost.com/business/2022/12/17/pediatric-bed-shortage-tripledemic-rsv-flu-covid/

Why parents are struggling to get hospital beds for kids with flu and RSV

Pediatric hospital beds are often empty and yield smaller reimbursements than adult care, making them targets for cost-cutting by hospitals.

The Washington Post

And LA County hospital beds are already at the lowest availability since the pandemic began:

https://www.latimes.com/california/story/2022-12-16/l-a-hospital-beds-at-lowest-availability-since-pandemic-began

L.A. County hospital beds drop to lowest availability of pandemic

The shortage is from rising cases of COVID-19, flu and RSV, as well as patients who have put off non-emergency care.

Los Angeles Times

We won't only see problems with hospital capacity, however. We've already experienced a shortage of fever-reducing and painkiller drugs, and China's new surge has triggered panic buying and new shortages:

https://edition.cnn.com/2022/12/21/economy/china-covid-chaos-global-run-medicine-hnk-intl/index.html

Do what you can to avoid infections with COVID or anything else in the weeks ahead because medications and hospital beds may be in short supply.

What happens next after BA5 becomes BQ becomes XBB in the US? Who knows? But COVID continues to mutate rapidly. And with 10% of the world's population likely to get infected in the next three months or so, experts fear a spectacular rise in the speed and diversity of new COVID mutations:

https://www.bloomberg.com/news/articles/2022-12-19/us-worries-china-s-covid-outbreak-could-lead-to-virus-mutations

I suspect we'll see still more immune-evasive variants rise in the US and elsewhere, so the pandemic is looking a long way from being over.

China’s Covid-19 Outbreak Has US Worried About New Variants

The US is concerned China’s runaway Covid-19 outbreak might spawn new mutations of the virus, as the world’s most populous country continues to grapple with the impact of loosening “Covid Zero” protocols that had kept the pandemic at bay.

Bloomberg
In 2023, not only will we see more infections, more mutations, and more surges, but we'll also learn more about what repeated COVID infections are doing to our bodies. While people continue to treat it like it's “just the flu,” there is growing evidence COVID inflicts longer-term harm on our immune systems:
https://www.therecord.com/news/waterloo-region/2022/12/20/immune-systems-seriously-weakened-by-covid.html
Immune systems seriously weakened by COVID

Evolving research says COVID leaves many people at heightened risk for other infections

The Star - BLOX QA4
Today, many cling to the idea the current “tridemic” of diseases is caused by so-called “immunity debt” or the â€śhygiene hypothesis,” but there is little evidence for this explanation. Sweden avoided lockdowns and isolation, yet it's suffering the same as elsewhere. Meanwhile, many Asian nations did have lockdowns, yet they aren't seeing the same“tridemic” as elsewhere (probably because they mask more commonly than we do in the West). 

People would rather believe our partial masking and brief and uneven isolation is causing today's rise of viruses because otherwise, they'd be force to change their behaviors. In fact, dozens of studies show COVID can harm the body's immune system, not to mention heart, brain and other systems long after infection and recovery:

https://docs.google.com/spreadsheets/d/12VbMkvqUF9eSggJsdsFEjKs5x0ABxQJi5tvfzJIDd3U/edit?usp=sharing

We won't be able to keep blaming immunity debt if 2023 continues to be a year of elevated viral and bacterial infections.

COVID-19/SARS-CoV-2 Studies - Google Drive

At some point, we'll have to face the fact that repeated COVID infections are dangerous, and that with COVID continuing to mutate, we'll need better solutions than merely ignoring it and trying to act normal. Those solutions may include new pan-coronavirus vaccines:

https://corporate.dukehealth.org/news/new-pan-coronavirus-vaccine-passes-key-experiments-demonstrates-protection

We also need new regulations governing safe filtration and ventilation in public buildings:

https://safety.blr.com/workplace-safety-news/hazardous-substances-and-materials/ventilation-indoor-air-pollution/COVID-19-task-force-calls-for-tougher-indoor-air-s/

New Pan-Coronavirus Vaccine Passes Key Experiments, Demonstrates Protection

DURHAM, N.C. – In laboratory and primate tests, a new pan-coronavirus vaccine developed by the Duke Human Vaccine Institute (DHVI) has demonstrated wide protection against SARS-CoV-2 viruses and variants, including Omicron BA.5.

Duke Health

And the other thing we require is more masking. We ought to treat masks like we do the weather--if the forecast calls for rain, we carry an umbrella; when the forecast calls for COVID, we put on a mask.

The forecast is for more COVID. New dangerous variants are growing, COVID in wastewater is rising, and the positive rate of testing is rising. Three-quarters of the US is at the highest level of COVID transmission, and another 16% is seeing substantial transmission:

https://covid.cdc.gov/covid-data-tracker/#county-view?list_select_state=all_states&list_select_county=all_counties&data-type=Risk

COVID Data Tracker

CDC’s home for COVID-19 data. Visualizations, graphs, and data in one easy-to-use website.

Centers for Disease Control and Prevention
There's zero reason to think you and your loved ones aren't at risk, so please put on a mask when you travel, reconsider crowded events, and think about testing before gathering with family and friends. Please enjoy a safe holiday season, and prepare for more COVID disruptions in 2023.
@augieray
Augie, avoiding COVID as much as possible is a dangerous thing to do. Sooner or later you will catch it. Later you catch it more harm it can cause, as your defence from vaccinations and booster diminishes with time.
@pws Completely incorrect. We know reinfections occur frequently. The goal is to hold off on getting it as much as possible, since it imparts no long-term immunity. Getting it sooner only means you're likely to get it more often, and studies show reinfections increase your odds of adverse outcomes. https://specialty.mims.com/topic/covid-19-reinfection-doubles-the-risk-of-death--
COVID-19 reinfection doubles the risk of death

COVID-19 reinfection doubles the risk of death and triples the risk of hospitalization, with post-acute sequelae in the pulmonary and extra-pulmonary ...

MIMS
@augieray Do not know where you have this idea from. Our entire history of medicine is proving differently:-(
@pws Every expert agrees with our entire history of medicine: You don't race to get flu or HIV to get it over with. You avoid getting ill. Repeated infections are very dangerous, and COVID reinfections can occur within a month or two of prior infection. You are wrong on the data, the science and the history.

@augieray @pws

Regrettably, quite true. Reinfection is not uncommon. Covid appears to suppress the immune system leading to further infections- not only Covid but other diseases as well. Repeated infections can cause increasing damage to organs. The risk of developing Long Covid is always there.
Not least of all, there are the people that one might inadvertently infect to consider as well.

I am doing my very, very best to avoid (another) reinfection. And I really wish others would too.