Delbruck found that bacteria size varied by a factor of three, but burst size varied across three orders of magnitude.

Delbruck noted "Comparison with the distribution of bacterial sizes in the same culture shows that the wide distribution of burst sizes cannot be accounted for by variations in the size of bacteria alone."

What, if not cell size, explained the massive intracellular differences in progeny production?

This question has been largely unaddressed since Delbruck's time.

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