Alan BerglandProud to share our latest work on seasonal evolution in Drosophila led by @jcbnunez. We show that the inversion In(2L)t changes in frequency between seasons, has captured old alleles and is also acquiring new beneficial ones, and is pleiotropic. (1/4)
Importantly, we inferred the phenotypic consequences of In(2L)t by aggregating >200 published phenotypes from the DGRP. In(2L)t is associated with dozens of phenotypes and we validated the effects of the inversion using fly genetics. (2/4)
And, we do it all after considering the effects of population booms during the summer and busts during the winter. Local effective population size is ~10,000 and yet population structure at the local scale is stable through time! (3/4)
This project uses a densely sampled time-series dataset from Virginia (USA) and also takes advantage of the DEST dataset (https://dest.bio) (4/4)