Fyodor UrnovDec 9, 2022
"Unless things change dramatically, the millions of people #CRISPR could save will never benefit from it. We must, and we can, build a world with #CRISPR for all."
https://www.nytimes.com/2022/12/09/opinion/crispr-gene-editing-cures.html
Opinion | CRISPR Can Cure Disease by Editing a Person’s DNA. Now What?

Revolutionized medicine may be at hand, but barriers remain.

The New York Times
Show threadJacob S. Sherkow 🦆💊🏸⚫Dec 9, 2022
@urnov Fyodor, this is excellent; clear, nuanced, concrete. On the regulatory side, rather than looking at CAR-T as the model, have you considered the EA N of 1 model used by Tim Yu for oligonucleotide therapy? May be at least a better starting point, especially if the mutation is very rare.
Show threadFyodor Urnov
@jsherkow Absolutely yes. Tim and the N=1 collaborative are a guiding light for us.
Dec 10, 2022 at 12:03amWeb