It's database update season (thanks to the NAR database issue)!

Progenomes 3 (>1 million annotated prokaryotic genomes, led by Daniel Mende): https://doi.org/10.1093/nar/gkac1078 https://progenomes.embl.de

eggNOG v6 (orthologs across 12k species, led by Jaime Huerta-Cepas) https://doi.org/10.1093/nar/gkac1022 http://eggnog6.embl.de

STRING v12 (protein–protein ixn networks across the same set of 12k species, led by Christian von Mering) https://doi.org/10.1093/nar/gkac1000 https://string-db.org