New in Exploring Mastodon:

The usual Twitter convention is to follow the whole person, meaning one Twitter account for a person would tweet on many different subjects. In the Fediverse, we see people having multiple Mastodon (and other) accounts.

https://martinfowler.com/articles/exploring-mastodon.html#multiple-mastodon-accounts

Exploring Mastodon

With the current uncertainty over Twitter, I'm starting to explore using Mastodon

martinfowler.com

@mfowler I am a Twitter multi-account user, as I wanted to differentiate personal stuff from work stuff, and also had a different one for gaming stuff. Now I realize that was a drawback that probably left me without the right number of followers.

However, on Mastodon the instance you choose might have an impact in whether you need multiple accounts or not, as some servers have rules of conduct that disallow people from tooting whatever they like (example, fosstodon toots should be Engilsh only)