Large Hadron Collider

Very Large Array

Quite Big Telescope

Moderately Enormous Antenna

Monstrous Magnifying Glass

Ludicrously Sized Observatory

Stonking Humungous Sky-Guzzler

Incomprehensibly Cyclopean Science Behemoth of Mind-Flaying Dimensions

A Pair Of Binoculars So Huge You Just Can't Imagine, They're Even Huger, No Far Bigger Than That, Now Double It

The Budget Eater

@natecull Phineas, Ferb, we need to talk
@natecull Hm... sounds about right for the most expensive experiments for physics/astrophysics.