Initial genomes from May 2026 Bundibugyo Virus Disease Outbreak in the Democratic Republic of the Congo and Uganda, reveal a new spillover event
On 15 May 2026, the Ministry of Public Health, Hygiene and Social Welfare, DR Congo (DRC) officially declared a Bundibugyo Virus Disease (BVD) outbreak in Ituri province, DRC. This represents 17th Ebola outbreak in DRC and the second #Ebola outbreak caused by Orthoebolavirus bundibugyoense (BDBV) species. After the 2007 outbreak in Bundibugyo, Uganda, and the 2012 BDV outbreak in Isiro, DRC, the ongoing outbreak is the third documented BDV outbreak.
The three newly generated #BDBV genome sequences from Uganda (one) and DRC (two) were analysed in the context of 34 BDBV genomes from the previous outbreaks in 2007 and 2012 downloaded from Pathoplexus.

