StructBiolCommunicationsThe NYN domain of human KHNYN was crystallized with a heptameric single-stranded RNA from the AU-rich elements of the 3′-UTR of interferon lambda 3, and the RNase activity and binding of the domain were demonstrated #KHNYN #ZAP #RNases https://t.co/kKzrIW6zXd
Crystallization and biochemical studies of the NYN domain of human KHNYN
The NYN domain of human KHNYN was crystallized with a single-stranded RNA and the crystal diffracted to 1.72 Å resolution. The RNase activity of the NYN domain was also demonstrated using different RNAs, together with the binding between the NYN domain of KHNYN and the zinc-finger domain of ZAP.