PLOS BiologyOrb2, the fly homolog of CPEB, forms #prion-like oligomers involved in maintenance of #LongTermMemory. This study identifies #Hsp40 family chaperone Mrj as a regulator of #Orb2 oligomerization and its association with translating ribosomes #PLOSBiology https://plos.io/4aRba2j
Mrj is a chaperone of the Hsp40 family that regulates Orb2 oligomerization and long-term memory in Drosophila
Orb2, the Drosophila homolog of CPEB, forms prion-like oligomers that play a crucial role in the maintenance of long-term memory. This study identifies the Hsp40 family chaperone Mrj as a regulator of Orb2 oligomerization and its association with translating ribosomes.
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