TAU researchers develop groundbreaking gene therapy to treat hearing, balance disabilities

“These findings highlight the potential of self-complementary AAVs to reduce dose requirements, minimize toxicity, and broaden clinical use…
#NewsBeep #News #Headlines #Genetherapy #genes #haircells #hearingandbalance #HearingLoss #IL #inner-ear #Israel #IsraelScienceFoundationBreakthroughResearchProgram #KarenAvraham #TelAvivUniversity #vestibularsystems
https://www.newsbeep.com/240776/

Découverte géniale dans un cabinet d'audioprothésiste : un livre pop-up sur l'audition qui illustre notamment la mise en mouvement des cellules ciliées par une onde sonore ! #audition #haircells #cochlea
Scientists use drug-like cocktail to regenerate hair cells in preclinical study

Effective hearing loss treatments have eluded medicine because once sensory cells in the inner ear called hair cells are damaged or destroyed, they cannot be regenerated. This loss of hair cells, which can be caused by aging, noise exposure and other factors, renders an individual's hearing loss permanent.

Medical Xpress
SIM & surface rendering reveals that #InnerEar #HairCells constantly supply #stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially #PLOSBiology https://plos.io/3GgF9mX
Control of stereocilia length during development of hair bundles

Lattice structured illumination microscopy and surface rendering reveals that inner ear hair cells constantly supply stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially.

SIM & surface rendering reveals that #InnerEar #HairCells constantly supply #stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially #PLOSBiology https://plos.io/3GgF9mX
Control of stereocilia length during development of hair bundles

Lattice structured illumination microscopy and surface rendering reveals that inner ear hair cells constantly supply stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially.

SIM & surface rendering reveals that #InnerEar #HairCells constantly supply #stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially #PLOSBiology https://plos.io/3GgF9mX
Control of stereocilia length during development of hair bundles

Lattice structured illumination microscopy and surface rendering reveals that inner ear hair cells constantly supply stereocilia building blocks to the hair bundle, but the unique protein composition at the tips of each row of stereocilia ensures that the rows grow differentially.

#HairCell Analysis Toolbox (HCAT) automates common image analysis tasks, e.g. counting & classifying #haircells, and determining optimal frequency. HCAT allows faster, unbiased & more comprehensive #cochlear image analysis @buswinka @IndArtur #PLOSBiology https://plos.io/3Z3Szte
The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification

This study presents the Hair Cell Analysis Toolbox (HCAT), which automates common image analysis tasks such as counting hair cells, classifying them by subtype and determining their optimal frequency. HCAT removes a considerable barrier in cochlear image analysis, allowing for faster, unbiased, and more comprehensive data analysis practices.

#HairCell Analysis Toolbox (HCAT) automates common image analysis tasks, e.g. counting & classifying #haircells, and determining optimal frequency. HCAT allows faster, unbiased & more comprehensive #cochlear image analysis @buswinka @IndArtur #PLOSBiology https://plos.io/3Z3Szte
The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification

This study presents the Hair Cell Analysis Toolbox (HCAT), which automates common image analysis tasks such as counting hair cells, classifying them by subtype and determining their optimal frequency. HCAT removes a considerable barrier in cochlear image analysis, allowing for faster, unbiased, and more comprehensive data analysis practices.

#HairCell Analysis Toolbox (HCAT) automates common image analysis tasks, e.g. counting & classifying #haircells, and determining optimal frequency. HCAT allows faster, unbiased & more comprehensive #cochlear image analysis @buswinka @IndArtur #PLOSBiology https://plos.io/3Z3Szte
The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification

This study presents the Hair Cell Analysis Toolbox (HCAT), which automates common image analysis tasks such as counting hair cells, classifying them by subtype and determining their optimal frequency. HCAT removes a considerable barrier in cochlear image analysis, allowing for faster, unbiased, and more comprehensive data analysis practices.