Right out of the @gordonconf on #fertilization2023, here's our latest baby:
https://www.biorxiv.org/content/10.1101/2023.07.27.550195
#fertilization #gamete_fusion #egg #sperm #JUNO #IZUMO1 #CD9 #SPACA6 #TMEM81 #AlphaFold
An #AlphaFold-Multimer screen of human proteins implicated in gamete fusion, carried out together with @arneelof, suggests that the fertilization synapse includes a complex of egg JUNO and CD9 and sperm IZUMO1, SPACA6 and TMEM81:



