Tom WilliamsJun 14, 2024

REMAP-CAP Steroids Trial Results about to be discussed (not in covid)

#CCR24

Tom WilliamsJun 13, 2024

HEMOTION Trial about to report results

HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN

#CCR24

Tom WilliamsJun 13, 2024
PREOXI Trial results, I find interesting how different the practice seems to be around the world. Mapleson C is standard of care in my region, cheap, quick to setup with some ability to dial in PEEP. Also easy to ventilate in the event of difficulties intubating.
Personally I gave up using NIV except in exceptional circumstances due to the complexity & effects it had on distracting the team from the task at hand.
#CCR24
Show threadKenneth BaillieJun 13, 2024
@DocEd well I think it’s fair to say this community led effort was quite idealistic and we haven’t recruited enough extroverts to get it going! But #CCR24 has reminded me how much great discussion we can have inside this community without needing the bigger audience that twitter offers
Kenneth BaillieJun 13, 2024
@DocEd interesting comment on twitter just now from you about misinterpreting frequentist CIs - could you give an example? I’m in the room at #ccr24 but I missed the transgression!
Ed PalmerJun 13, 2024
Putting #SPICE3 together with #A2Btrial it does now seem hard to justify the use of these drugs in the ICU. I’m not very compelled by the arguments that we should try again with even higher doses given the side effect profile of these agents. #CCR24
Show threadKenneth BaillieJun 13, 2024
@Watergypsy Very interesting that the interaction with age that SPICE3 reported seemed to be completely absent in A2B. #CCR24
Show threadTom WilliamsJun 13, 2024
Another nicely designed & run trial that is unlikely to change my practice. Dexmed to help bridge extubation maybe a good future direction, using it early seems to require quite a lot of propofol!
#CCR24 #A2B
Tom WilliamsJun 13, 2024

A2B Trial results about to report at #CCR24

PROPOFOL VS DEXMEDETOMIDINE VS CLONIDINE

Tom WilliamsJun 12, 2024

Protection trial

Just published in NEJM

https://www.nejm.org/doi/full/10.1056/NEJMoa2403769

#CCR24