Mastodawn

🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

Holly 2d ago

How red-light therapy really works. It's not just for serial traffic violators any more

https://www.nature.com/articles/d41586-026-00878-1?utm_source=fark&utm_medium=website&utm_content=link&utm_campaign=fark&ICID=ref_fark

#stem #science #health #biophysics #physiology #cool

The surprising science behind red-light therapy — and how it really works

People are buying helmets, face masks, vests and beds that emit long-wavelength light. Beneath the hype, there is some interesting biology.

Scientific Frontline 3d ago

Researchers have developed microscopic glass bead lasers—measuring between 0.1mm and 0.01mm—capable of acting as highly sensitive optical biosensors. These #microlasers can detect materials at an unprecedented scale, identifying individual molecules and single atomic ions.
#OpticalPhysics #Biophysics #Biochemistry #MedicalDiagnostics #Photonics #sflorg
https://www.sflorg.com/2026/03/phy03252601.html

First microlasers capable of detecting individual molecules and ions could one day aid diagnosis

Microlasers are tiny glass beads measuring around just 0.1 mm (the width of a human hair) to 0.01mm – (the length of a single bacterium).

Patrick van der Wel 3d ago

Looks like a great @[email protected] workshop coming in September: “Lipid Code to Life”, with a who’s who of lipid #biochemistry… (e.g. @[email protected] @[email protected] @[email protected] etc ) More info and registration: meetings.embo.org/event/26-lip... #lipids #biophysics

Lipid Code to Life

European Physical Society(EPS)4d ago

Call for Contributions – Biology for Physics 2026

Submit your abstract to this conference at the physics–biology interface. Topics include energy & information in biology, noise in cells/brains, molecular machines, entropy & information–energy conversion, and development dynamics.

Submit: https://www.biologyforphysics.org/

#CallForPapers #Biophysics #PhysicsOfLife

katch wreck 4d ago

`Surprisingly..extracted diffusion coefficient at the free energy barrier on the number of native contacts coordinate increases with protein length. This facilitation..in larger proteins is explained by increased cooperative native contact formation during folding, which reduces the roughness of the energy landscape... evolutionary optimization of the energy landscape..more efficient for protein folding than for other biomolecular processes`
https://doi.org/10.1103/2q9m-4scc
#proteinFolding #biophysics

jobRxiv 5d ago

Postdoc Position at MSU in Ultrafast Science
Michigan State University

See the full job description on jobRxiv: https://jobrxiv.org/job/michigan-state-university-27778-postdoc-position-at-msu-in-ultrafast-science/

#biophotonics #biophysics #biosensors #methoddevelopment #microscopy #nanoscience #Ultrafastscience #virology #ScienceJobs #hiring #research
https://jobrxiv.org/job/michigan-state-university-27778-postdoc-position-at-msu-in-ultrafast-science/?fsp_sid=10593

Postdoc Position at MSU in Ultrafast Science

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv

Nithin C 5d ago

Our new paper published in the Computational and Structural Biotechnology Journal explains how ligands binding the exact same IL1R1 site produce opposite outcomes.

We used MD simulations and CABS-flex to show how IL1 receptor antagonists block signaling despite binding the exact same site as agonists. Instead of a static blockade, antagonists actively disrupt distal D3 domain dynamics.

Read here: https://doi.org/10.34133/csbj.0017

#MolecularDynamics #Biophysics #StructuralBiology #Allostery

CSBJ 6d ago

🧱 What if activation and inhibition are not about binding but about motion?

🔗 Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines

Johannes W. Dietrich Mar 20

Mathematical modelling, computer #simulation, and machine learning upgrade #endocrinology. Applying principles of #biocybernetics and #biophysics, they enjoy growing interest and deliver novel methods for research, diagnosis, and therapy.

https://pubmed.ncbi.nlm.nih.gov/41852474/
https://doi.org/10.3389/fendo.2026.1806508