Atlas of the anatomical localization of atypical chemokine receptors in healthy mice

Atypical chemokine receptors (ACKRs) scavenge chemokines and can contribute to gradient formation by binding, internalizing and delivering chemokines for lysosomal degradation. This study provides an atlas of expression of ACKRs using fluorescent reporter mice and specific chimeric chemokines, revealing patterns of expression and co-expression in the endothelium of various organs.