121 Followers
285 Following
148 Posts
Reader in Synthetic and Molecular Biology | Cell-Free Systems | Bioprogrammable Materials | Metabolic Engineering
Webhttps://www.ncl.ac.uk/nes/people/profile/thomashoward.html
JobReader in Synthetic and Molecular Biology
LocationMolecular Life Sciences Newcastle University

@TheBreadmonkey

In the voice of Sir David Attenborough:

'Welcome to the digital undergrowth. A place far away from the screeching X-site and the bile of Meta.

Behold the Mastodon user! Shhh. Don’t startle them with a promoted post or an algorithmic 'For You' feed. They are sensitive to such disturbances.

Truly, they are the kindest of the great apes. A rare, decentralised species that has looked at the chaos of the modern world and decided, quite simply, to be... pleasant.'

The Journal of Open Source Software (@joss) turns 10 today!

Ten years, 3,500+ papers, 11,000+ authors, 4000+ reviewers, and a community that built something remarkable together. Thank you to everyone who's reviewed, edited, authored, or cheered us on along the way 💚

https://joss.theoj.org #openscience #opensource

Journal of Open Source Software

Journal of Open Source Software (JOSS) is a developer friendly, open access journal for research software packages.

Final week of our Python course for Plant Sciences Master’s students 🌱🐍🖥️
Covered fundamentals (data types, control flow), file handling, and modules, plus discussed the risks and benefits of AI in scientific research.

🔗 https://github.com/bpucker/PyBo

#Python #PlantScience #Bioinformatics #DataScience #HigherEducation
@PuckerLab
@samnm

🌸 Do you enjoy cherry blossoms?

We are looking for a future group member to explore the genetic mechanisms behind coloration in cherry flowers and fruits.

The project focuses on tissue-specific gene expression and its role in ornamental plants and crops.

🔗 Details: https://www.izmb.uni-bonn.de/en/pbb/teaching#cherry

#PlantScience #Genetics #Botany #AcademicJobs #Research
@PuckerLab
@samnm

When a gene is transcribed, it creates physical ripples along the DNA strand that can either activate or suppress neighboring genes. The physical ordering and arrangement of these genes, known as "gene syntax," directly dictates how their structural interactions couple their expression.
#SyntheticBiology #Biophysics #Genetics #ChemicalEngineering #sflorg
https://www.sflorg.com/2026/04/sybi04302601.html
Gene circuits reshape DNA folding and affect how genes are expressed

Discover how gene syntax and physical DNA folding changes, like supercoiling, allow scientists to biophysically control synthetic gene circuits.

@Canageek @Fiona

Okay! Phosgene (COCl2). Smells like fresh hay (ah!). You breath in and it's completely fine... until 12–24 hours pass and your lungs fill with fluid and ..the kicker! ... there's no antidote. WWI chemical warfare was merciless in large part because of that.

But it's also incredibly boring. Millions of tons of it are produced annually for polycarbonates and polyurethanes. It's also overwhelmingly present in every undergraduate textbook -- and hell, even high school ones too.

As a practical danger bonus: our whole institute was evacuated once because someone found a forgotten few-liter tank shoved into a service duct (yeah, that apparently happens). Nobody knew how long it had been there. 🙃

How about we play a game:

The first person names a chemical substance and gives an overview as to all the ways in which it is dangerous. The next person then has to come up with something even more dangerous.

Physical dangers (usually stored in pressured containers, inert gas that presents a danger of asphyxiation, …) don’t count, and the same holds for anything regarding radioactivity.

Also: Huge bonus for diversity and practical danger: A lot of substances can explode, but ones that do it without much convincing and produce poison-gas, or fires that are inextinguishable, or cause cancer, yet are stable enough to actually see real world use are much more interesting.

#chemistry
Entire NSF science advisory board fired by Trump administration

Members of the National Science Board, which the US Congress founded in 1950, were given no explanation for their termination

Scientific American

The Onion have finally completed their takeover of InfoWars, and it's everything I wanted and more.

https://theonion.info/

InfoWars

Let me tell you a story. When I was a child, I suffered from night terrors. It was always the same dream: I could hear my family and neighbors wailing…

InfoWars
Goooooood morning Fedinaaaaaaaaam! I hope you are literally better than terrific this morning. So good it almost hurts but in that good sexy way (sorry to say sexy on the internet). For some reason known only to the christ-child, who is coming to save us from.... *checks notes*.... the people who worship him?....... I've been up and at 'em since just after 5. Dunno why. Just happens sometimes. I am full of vim and vigor and have cleaned the kitchen, had breakfast with two espressos, done the ironing, applied for 3 jobs and watched the news (don't bother). I am a machine! An unstoppable machine! I *might* have had too much coffee. Or I am the messiah. Either is equally possible. Right I'm off to sort my life out for #ParkRun then have an absolute roller coaster of a day with a replacement washing machine and 8 loads of washing. Hurrah! I love you. The end. X