Dr. Sven-Eric Jordt

@sejordt
161 Followers
320 Following
48 Posts
Assoc Prof @Duke_Anesthesia, @Duke_PCB @dukeu . Fights against chemicals that hurt you. Views my own. #BLM #StopAsianHate #VaccinesWork 🇺🇸 🇩🇪 🇺🇦

Research on #Pain #Itch #ChemicalSenses #TRP #TRPA1 #TRPV1 #TRPM8 #GPCR #DRG #Trigeminal #Vagus #Neuroscience #Neurobiology #TearGas #Nicotine #TobaccoControl #Toxicology #Flavor #Menthol #Ecigs #E-cigarettes #MentholBan #ARDS #Asthma #ALI #Lung
#ImWithFauci

Interessante und sehr unterhaltsame Dokumentation zum Thema "So MÄCHTIG ist die Tabak-Lobby"

https://www.youtube.com/watch?v=GWrpHuOUV3A

So MÄCHTIG ist die Tabak-Lobby

YouTube
"The projected number of smokers who would quit after a US menthol ban would be 789 724 daily smokers (including 199 732 African Americans) and 1 337 988 daily+non-daily smokers (including 381 272 African Americans)."
https://tobaccocontrol.bmj.com/content/early/2022/04/27/tobaccocontrol-2021-057227.long
Impact of Canada’s menthol cigarette ban on quitting among menthol smokers: pooled analysis of pre–post evaluation from the ITC Project and the Ontario Menthol Ban Study and projections of impact in the USA

Introduction Between 2015 and 2018, Canada banned menthol cigarettes. This study pooled data from two pre–post cohort studies (the Ontario Menthol Ban Study, and the International Tobacco Control Policy Evaluation (ITC) Canada Survey, conducted in seven provinces) to derive more precise estimates of the impact of Canada’s menthol ban on quitting and to apply these estimates to project the impact of a menthol ban in the USA. Methods Weighted multivariable logistic analyses compared post-ban quit success of menthol smokers with non-menthol smokers (for daily smokers and for all (daily + non-daily) smokers), controlling for sex, age, ethnicity, education, baseline smoking status, baseline cigarettes per day and study regions. Projections to the USA were created by multiplying the effect size of the Canadian menthol ban on quitting (percentage of increased quitting among menthol smokers) by the number of menthol smokers overall and among African Americans, from the 2019 National Survey on Drug Use and Health. Results After the menthol cigarette ban, menthol smokers were more likely than non-menthol smokers to have quit smoking among daily smokers (difference=8.0%; 95% CI: 2.4% to 13.7%,p=0.005) and all (daily+non-daily) smokers (difference=7.3%; 95% CI: 2.1% to 12.5%,p=0.006). The projected number of smokers who would quit after a US menthol ban would be 789 724 daily smokers (including 199 732 African Americans) and 1 337 988 daily+non-daily smokers (including 381 272 African Americans). Conclusions This pooled analysis of Canada’s menthol cigarette ban provides the foundation for estimating the impact of menthol bans in the USA and other countries. Projections suggest that a US menthol cigarette ban would have a substantial impact on increasing quitting. Data are available upon reasonable request. Data are available upon reasonable request. In each country participating in the International Tobacco Control Policy Evaluation (ITC) Project, the data are jointly owned by the lead researcher(s) in that country and the ITC Project at the University of Waterloo. Data from the ITC Project are available to approved researchers 2 years after the date of issuance of cleaned data sets by the ITC Data Management Centre. Researchers interested in using ITC data are required to apply for approval by submitting an International Tobacco Control Data Repository (ITCDR) request application and subsequently to sign an ITCDR Data Usage Agreement. The criteria for data usage approval and the contents of the Data Usage Agreement are described online (<http://www.itcproject.org>).

Tobacco Control
Each month the US FDA delays the menthol cigarette ban, many 1000s of children and young people will start smoking menthols, and chronic menthol smokers will make less quit attempts.
Menthol cigarettes were responsible for 1.5 million new smokers, 157 000 smoking-related premature deaths and 1.5 million life-years lost among African Americans over 1980–2018.
https://tobaccocontrol.bmj.com/content/31/4/569
Consequences of a match made in hell: the harm caused by menthol smoking to the African American population over 1980–2018

Background For many years, national surveys have shown a consistently disproportionately high prevalence of menthol smokers among African Americans compared with the general population. However, to our knowledge, no prior study has quantified the harm that menthol smoking has caused on that population. In this work, we estimate the public health harm that menthol cigarettes have caused to the African American community over the last four decades. Methods Using National Health Interview Survey data, we employed a well-established simulation model to reproduce the observed smoking trajectory over 1980–2018 in the African American population. Then, we repeat the experiment, removing the effects of menthol on the smoking initiation and cessation rates over that period, obtaining a new hypothetical smoking trajectory. Finally, we compared both scenarios to calculate the public health harm attributable to menthol cigarettes over 1980–2018. Results Our results show that menthol cigarettes were responsible for 1.5 million new smokers, 157 000 smoking-related premature deaths and 1.5 million life-years lost among African Americans over 1980–2018. While African Americans constitute 12% of the total US population, these figures represent, respectively, a staggering 15%, 41% and 50% of the total menthol-related harm. Discussion Our results show that menthol cigarettes disproportionally harmed African Americans significantly over the last 38 years and are responsible for exacerbating health disparities among that population. Removing menthol cigarettes from the market would benefit the overall US population but, particularly, the African American community.

Tobacco Control
The US FDA missed their self-imposed deadline to finalize their rule to ban menthol cigarettes. Menthol cigarettes were responsible for 10.1 million extra smokers, 3 million life years lost and 378,000 premature deaths between 1980 and 2018.
https://ash.org/joint-statement-fda-continues-to-delay-2023/
Joint Statement: The FDA Continues to Delay Protecting Americans from Mentholated Cigarettes

The FDA Continues to Delay Protecting Americans from Mentholated Cigarettes August 2023 was the deadline announced by FDA to propose a rule WASHINGTON, DC – AUGUST 31, 2023 – The U.S. Food and Drug Administration (FDA) missed their self-imposed deadline to propose a life-saving rule to ban menthol as a characterizing flavor in combustible cigarettes. [...]

ASH > Action on Smoking & Health
My parents, survivors & Refugees taught me this #Holocaust lesson: if you find yourself among the privileged - #RememberWhereYouCameFrom, support the poor, the sick, the dispossessed, the disadvantaged. I spoke about that at my Amberson Award at #ATS2022
https://youtu.be/3xSN-L5GWWk?t=249
ATS 2022 J. Burns Amberson Lecture

YouTube

Avoidable public health disaster in Germany: Smoking rate among 14-17 year olds has doubled in 2022, from 8.7% - 15.9%, according to DEBRA study directed by @danielkotz
. 200,000 more underage smokers in one year !

https://www.spiegel.de/gesundheit/rauchen-hunderttausende-jugendliche-in-deutschland-greifen-zur-zigarette-a-8eba30ed-903a-41a7-997c-e8a2e2291177

Zigarettenboom in Deutschland: Hunderttausende Jugendliche fangen mit dem Rauchen an

Im vergangenen Jahr hat sich der Anteil der Raucherinnen und Raucher unter den 14- bis 17-Jährigen fast verdoppelt, ergibt eine neue Studie. Gesundheitsminister Lauterbach zeigt sich entsetzt.

DER SPIEGEL
Everything for the birbs!

This is so interesting:
https://www.cell.com/cell-reports/fulltext/S2211-1247(21)01802-7
Synaptically connected neurons send proteins to each other packaged in exosomes. Previous studies showed protein transfer but I think this is the first large-scale screen, identifying 200 proteins (likely an underestimate because they only looked at ones passing through axons).

More evidence that our conventional models of neural signaling are radically incomplete!

Today, FDA CTP published a new infographic highlighting the key findings from the 2022 National Youth Tobacco Survey.

https://digitalmedia.hhs.gov/tobacco/print_materials/CTP-229

2022 NYTS All Tobacco Findings Infographic - Tobacco Education Resource Library Print Materials & Downloads