Guix fixed most of the vectors of supply chain attack, before supply chain attacks became a mainstream :)
Guix fixed most of the vectors of supply chain attack, before supply chain attacks became a mainstream :)
Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice:
https://www.nature.com/articles/s41593-025-02199-4
Data in https://genenetwork.org/

Alzheimer’s disease alters brain structure broadly, but its regional impact is poorly mapped. Here, the authors show that App and Psen1 mutations in mice cause volume changes across 231 regions, which are associated with individual differences in behavior.
raven-uxn now has an x86-64 assembly backend (yay!)
and it's about 2x faster (yay!!)
and the first draft was written by Claude (booo!)
and then I rewrote most of it, which made it even faster (yay!)
and introduced a memory corruption bug (booo?)
which Claude is better at debugging than I am (.......?)
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if you too have complicated feelings about our robot buddies, you may enjoy my writeup:
RE: https://social.coop/@spritely/116132867771534636
Worked pretty hard on this one and I'm proud of the milestone! Lots more to do for a truly ergonomic dev experience but finally having the REPL in the browser is a huge deal.
The annual Guix-HPC report was published last Friday, check it out!
https://hpc.guix.info/blog/2026/02/guix-hpc-activity-report-2025
Home from #fosdem and #guixdays had an absolute blast! Thank you everyone for the great conversations and companionship!
Excited to be organizing next years Guix Days and the Declarative and Minimalistic Computing 🎉
Big thanks to @pjotrprins and @mragkousis for their hard work organizing both these wonderful events this year!🙌
Today I'm catching up on work, but I look forward to soliciting the community for additional help! It takes a village!
See y'all next year and hope to stay in touch!