Pjotr Prins

@pjotrprins
151 Followers
91 Following
463 Posts

Guix fixed most of the vectors of supply chain attack, before supply chain attacks became a mainstream :)

#guix

Mail server at Hertzner runs 3 years uninterrupted. I know, it should be Guix ;)

Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice:

https://www.nature.com/articles/s41593-025-02199-4

Data in https://genenetwork.org/

Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice - Nature Neuroscience

Alzheimer’s disease alters brain structure broadly, but its regional impact is poorly mapped. Here, the authors show that App and Psen1 mutations in mice cause volume changes across 231 regions, which are associated with individual differences in behavior.

Nature
Debian decides not to decide on AI-generated contributions...

raven-uxn now has an x86-64 assembly backend (yay!)

and it's about 2x faster (yay!!)

and the first draft was written by Claude (booo!)

and then I rewrote most of it, which made it even faster (yay!)

and introduced a memory corruption bug (booo?)

which Claude is better at debugging than I am (.......?)

--------

if you too have complicated feelings about our robot buddies, you may enjoy my writeup:

https://www.mattkeeter.com/blog/2026-03-15-uxn/

An x86-64 backend for raven-uxn

Porting 2000 lines of ARM64 assembly to x86-64, with the help of a robot buddy

The free software world pretty much ignored AI until this year. With all the recent (re)active posting on AI I reckon there must be some real value in using the tools for coding.

RE: https://social.coop/@spritely/116132867771534636

Worked pretty hard on this one and I'm proud of the milestone! Lots more to do for a truly ergonomic dev experience but finally having the REPL in the browser is a huge deal.

Home from #fosdem and #guixdays had an absolute blast! Thank you everyone for the great conversations and companionship!

Excited to be organizing next years Guix Days and the Declarative and Minimalistic Computing 🎉

Big thanks to @pjotrprins and @mragkousis for their hard work organizing both these wonderful events this year!🙌

Today I'm catching up on work, but I look forward to soliciting the community for additional help! It takes a village!

See y'all next year and hope to stay in touch!

Great talk (and demos!) by @wingo on compiling wasm to native via C.

Looking forward to the Scheme->wasm->native pipeline in #Guile. :-)