I’m specifically looking for:
• experimental collaborators, especially for:
– patch-clamp or chloride imaging in ventral CA1 slices
– in vivo mouse ventral CA1 physiology (γ synchrony, firing thresholds, replay probability)
I am genuinely open to strong criticism, alternative interpretations, and any kind of discussion or collaboration.
8-minute summary video: https://youtu.be/KATz458x_Cw
#depression #ptsd #autism #alzheimer #adhd #neuroscience #research #psychiatry #addiction
What do you think about a new hypothesis on the mechanism underlying psychiatric and neurodegenerative disorders?
In short, the model proposes that many different conditions may arise from a single process — a narrowing of the neuronal “excitability margin” (ΔVmargin).
🎥 8-minute video summary:
https://youtu.be/KATz458x_Cw
🔗 Preprint (OSF):
https://osf.io/preprints/osf/e4cwb_v3
🔗 Independent PREreview (positive):
https://prereview.org/reviews/17196364
#neuroscience #psychiatry #depression #autism #alzheimer #research #brain
One mechanism may underlie schizophrenia, depression & PTSD: ΔVmargin collapse in vCA1. Independently confirmed by a PREreview.
Video: https://youtu.be/KATz458x_Cw
Paper: https://osf.io/e4cwb
Review: https://prereview.org/reviews/17196364
#mentalhealth #neuroscience #psychiatry #autism #depression #research
@psychiatry
@technologyreview
@harvardhci
@AllenInstitute
@neuroscience
@nature
🚨 Breakthrough preprint independently reviewed!
The unified mechanism for schizophrenia, depression & PTSD — now validated via PREreview (Zenodo).
📄 https://osf.io/e4cwb_v3
🔗 https://prereview.org/reviews/17196364
🎥 Short explainer (9 min): how excitability-margin collapse in ventral CA1 could unify PTSD, depression & schizophrenia.
🔗 https://youtu.be/DWbEN-F5MLY
#Neuroscience #Psychiatry #PTSD #Depression #Schizophrenia #OpenScience #MentalHealth
🚨 Breakthrough preprint independently reviewed!
The unified mechanism for schizophrenia, depression & PTSD — now validated via PREreview (Zenodo).
📄 https://osf.io/e4cwb_v3
🔗 https://prereview.org/reviews/17196364
🎥 Short explainer (9 min): how excitability-margin collapse in ventral CA1 could unify PTSD, depression & schizophrenia.
🔗 https://youtu.be/DWbEN-F5MLY
#Neuroscience #Psychiatry #PTSD #Depression #Schizophrenia #OpenScience #MentalHealth
🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
🎥 9-min explainer video: https://www.youtube.com/watch?v=DWbEN-F5MLY
🔗 Full preprint: https://osf.io/preprints/osf/e4cwb_v3
#Neuroscience #Psychiatry #MentalHealth #Schizophrenia
#Depression
#PTSd
#OpenScience #BrainHealth
🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
🎥 9-min explainer video: https://www.youtube.com/watch?v=DWbEN-F5MLY
🔗 Full preprint: https://osf.io/preprints/osf/e4cwb_v3
#Neuroscience #Psychiatry #MentalHealth #Schizophrenia
#Depression
#PTSd
#OpenScience #BrainHealth
🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
🎥 9-min explainer video: https://www.youtube.com/watch?v=DWbEN-F5MLY
🔗 Full preprint: https://osf.io/preprints/osf/e4cwb_v3
#Neuroscience #Psychiatry #MentalHealth #Schizophrenia
#Depression
#PTSd
#OpenScience #BrainHealth
🚨 New hypothesis: One mechanism links schizophrenia, depression & PTSD: collapse of excitability margin (ΔVmargin) in ventral CA1.
🎥 9-min explainer video: https://www.youtube.com/watch?v=DWbEN-F5ML
🔗 Full preprint: https://osf.io/preprints/osf/e4cwb_v3
#Neuroscience #Psychiatry #MentalHealth #Schizophrenia #Depression #PTSD #OpenScience #FediSci
