Pathoplexus

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An open-source pathogen sequence database dedicated to equitable sharing, transparent governance, & empowering global public health.
websitehttps://pathoplexus.org/
9/ 🛠️ More tech:
- Improved group management - warnings for duplicate group names & easier ways to find & join existing groups
- Expanded measles dataset via higher-level INSDC taxon ingestion (thanks to Jover Lee for the tip!)
8/ 🛠️ Tech improvements:
- Reverse complement retries now boost alignment success
- New CCHF dataset with lineages for the S segment
- Simpler multi-segment upload with the new fastaIds field
- Mutation search redesigned for segmented viruses - no need to append segment name!
5/ 🧫 On the first full-genome measles sequences from Senegal, Dr Idrissa Dieng (Institut Pasteur de Dakar) noted: "By sharing through Pathoplexus, we ensure that African-generated data are visible, valued, and integrated into international public health action." 🌍

1/ 🦟 Big news: #Pathoplexus now supports Dengue virus & Yellow Fever virus - two arboviruses responsible for over 400 million infections and up to 94,000 deaths per year.
Here's what’s new in our latest update 👇🏻

Read the full update: https://pathoplexus.org/news/2026-03-12-expanding-pathoplexus-arbos 📰

1/ 🚀 Pathoplexus now supports Marburg virus (MARV) and Ravn virus (RAVN) (sister viruses in the same genus). MARV has two main clades and causes severe disease with reported fatality rates of 24–88%.

You can read more detail about adding Marburg here: https://pathoplexus.org/news/2025-11-28-expanding-pathoplexus-marburg

8/ 🎤 Talks & media:

We’ve been on the road!
• A 2-part Pathoplexus feature on the MicroBinfie Podcast
• Tutorials at BC2, presentations at the IMMEM conference & the PHA4GE Conference & pre-workshop

Next up: See us at the Viruses in Silico lecture series (27 Nov 16:00 CET)

7/ 🛠️ Tech improvements (cont.):

• Better UI banners for restricted sequences
• A new “Tools” tab - which highlights external apps/tools that use Pathoplexus data! If you’ve built one and want yours included, let us know! 👂🏻

6/ 🛠️ Tech improvements:

• Support for accented characters in author names
• New means2id field for measles sequence upload, linking to the MeaNS2 database
• Improved groups pages highlight uploads per pathogen
• Multiple choice searches for better filtering!

1/ 🚀 Big thanks to our community - since August we’ve added thousands of new sequences, rolled out major new features, and welcomed fresh faces into the #Pathoplexus world. Let’s dive into what’s new.👇🏻

Read the full update: https://pathoplexus.org/news/2025-11-18-november-update

Since these sequences are likely to attract interest, it’s worth highlighting again what ‘Restricted-Use’ means on Pathoplexus.

Data Use Terms for Restricted-Use data: https://pathoplexus.org/about/terms-of-use/data-use-terms#42-restricted-data-use

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